Mafioso is an indica strain crossed from Bubba kush X ( Slymer x Thinmint Cookies) genetics. Mafioso offers a loud berry and grape flavor that’s backed by sharp lemon and citrus overtones. In terms of effects, you can expect a head and body high that will leave you blissed out on the couch. Medical marijuana patients choose this strain to relieve symptoms associated with fatigue and depression.